Anish G. Ghodadra, MD

Research and Publications

Dr. Ghodadra's research spans interventional oncology outcomes, Genicular Artery Embolization, 3D printing in medicine, and imaging biomarkers. A complete bibliography is available on PubMed. For the projects currently underway and the people running them, see the Ghodadra Lab.

Clinical Trials and Investigator Roles

NCT04951479 (GAE for Knee Osteoarthritis): Dr. Ghodadra is the named Sponsor-Investigator of this completed UPMC trial evaluating Teleflex Gel-Bead embolic particles for the treatment of osteoarthritis-related knee pain.

Additional GAE-related trials referenced in the field include: NCT04472091, NCT04682652, NCT05386797, and NCT06514755 (the latter a sequential genicular nerve ablation plus GAE trial). Refer to ClinicalTrials.gov for current protocols and enrollment status.

Selected Publications

A full bibliography is available on PubMed (search: "Ghodadra A" and "Ghodadra AN"). Notable peer-reviewed work includes:

  • Pathophysiology of Knee Osteoarthritis and Mechanisms of Genicular Artery Embolization for Interventional Radiologists. Journal of Vascular and Interventional Radiology, 2025 (co-author).
  • Key Osteoarthritis Biomarkers: What Interventional Radiologists Performing Genicular Artery Embolization Need to Know. (Chlorogiannis D, Ghodadra A, et al.)
  • Yttrium-90 Radioembolization Is Cost Effective in Intrahepatic Cholangiocarcinoma: A SEER Medicare Population Study. Journal of Vascular and Interventional Radiology, 30(3), 2019.
  • Abscopal Effects and Yttrium-90 Radioembolization. CardioVascular and Interventional Radiology, 39(7), 2016.
  • RSNA 3D Printing SIG: Clinical Situations for Which 3D Printing Is Considered an Appropriate Representation or Extension of Data Contained in a Medical Imaging Examination: Vascular Conditions. 3D Printing in Medicine, 2023.
  • 3-Dimensional Printed Models May Be a Useful Tool When Planning Revision Anterior Cruciate Ligament Reconstruction. Arthroscopy, Sports Medicine, and Rehabilitation, 2019.
  • Evaluation of 3D Printed Temporal Bone Models in Preparation for Middle Cranial Fossa Surgery. Otology and Neurotology, 2019.
  • Safety of Drilling 3-Dimensional Printed Temporal Bones. JAMA Otolaryngology Head and Neck Surgery, 144(9), 2018.
  • Lung Shunt Fraction Prior to Yttrium-90 Radioembolization Predicts Survival in Patients with Neuroendocrine Liver Metastases. CardioVascular and Interventional Radiology, 2016.
  • Connecting cancer biology and clinical outcomes to imaging in KRAS mutant and wild-type colorectal cancer liver tumors following selective internal radiation therapy with yttrium-90. Abdominal Radiology, 2017.
  • Sestamibi SPECT/CT versus SPECT only for preoperative localization in primary hyperparathyroidism: a single institution 8-year analysis.
  • Principle Component Analysis of Diffusion Tensor Images to Determine White Matter Injury Patterns Underlying Post-Concussive Headache. American Journal of Neuroradiology, 2016.

3D Printing Research

Dr. Ghodadra is a co-author on multi-society RSNA Special Interest Group consensus papers establishing appropriate clinical situations for 3D printing in radiology, including vascular conditions, abdominal and hepatobiliary conditions, and document control workflows for point-of-care 3D printing. The UPMC 3D Printing Program produces patient-specific anatomic models, surgical guides, and pre-procedural simulators across surgical and interventional services.

Honors and Awards

  • RSNA Roentgen Resident/Fellow Research Award (2016)
  • World Congress on Interventional Oncology Resident Scholarship (2015 and 2016)
  • American Society of Neuroradiology Trainee Award (2015)
  • AUR Radiology Resident Academic Leadership Development Program Scholarship (2015)
  • Phi Delta Epsilon International Medical Fraternity, Shipley Glick Award for Outstanding Medical Member (International Convention 2012)

Recent GAE Field Developments (2024–2026)

  • SIR Reporting Standards (Ahmed et al., JVIR 2024): Harmonize how future GAE trials should report endpoints, embolic specifications, and adverse events.
  • GENESIS 2: Double-blind, sham-controlled randomized trial expected to provide definitive efficacy evidence.
  • MOTION trial: Multicenter randomized comparison of GAE with Embosphere microspheres to corticosteroid injections.
  • GENI trial: Randomized comparison of GAE to genicular neurolysis.
  • LipioJoint and GAUCHO: International trials further mapping GAE's place among standard knee OA therapies.
  • Imaging-guided patient selection: Dynamic contrast-enhanced MRI and synovitis biomarker scoring (WORMS, Hoffa-synovitis) being explored to better predict responders.
  • Embolic agent innovation: Permanent microspheres compared with temporary agents (IPM/CS, resorbable gelatin microspheres, Gel-Bead) in size ranges from 75 to 300 microns.
  • Expanding indications: Beyond knee OA and hemarthrosis, GAE-style transarterial embolization is being studied for adhesive capsulitis, tendinopathies, and other inflammatory musculoskeletal pain conditions.

Professional Society Memberships

  • Society of Interventional Radiology (SIR)
  • Radiological Society of North America (RSNA)
  • Society of Interventional Oncology (SIO)
  • Phi Delta Epsilon International Medical Fraternity (founding member, Epsilon Epsilon chapter; former International Fraternity Board President)

Media and News

  • UPMC HealthBeat (June 2025): "Myra's Story: GAE for Hemarthrosis." Featured patient narrative in which Dr. Ghodadra performed two GAE procedures for an 82-year-old woman with recurrent hemarthrosis after a 2019 right knee replacement.
  • UPMC patient education page on Genicular Artery Embolization (last reviewed 2025-02-04 by Anish Ghodadra, MD).
  • News features on his role in advancing medical 3D printing, including coverage in industry outlets such as In Medical 3D Printing, a Bright Future Is Taking Shape (2019).